Review Article

Jan - Feb 2018  |  Vol: 4  |  Issue: 1
Vitamin D: Deficiency, Emerging Roles in Various Diseases, Metabolism, Supplementation, Treatment Strategies, Serum Levels and Dosage Recommendation

Sagar Kishor Savale*

*Department of Pharmaceutics, R. C. Patel Institute of Pharmaceutical Education and Research, Shirpur 425405, Maharashtra, India


* Corresponding author,

Mr. Sagar Kishor Savale,

Department of Pharmaceutics,

R. C. Patel Institute of Pharmaceutical

Education& Research, Shirpur, 425405,

 Maharashtra, India.Mobile No: 9960885333,

Email ID:




Objective: Vitamin D has been found to be useful for a number of conditions. Various studies have found it useful in different disorders to varying degree. It is being prescribed very frequently in clinical practice. So, we decided to conduct review to clarify its role in prevention and treatment of different disorders. We found vitamin D to be efficacious in conditions like cardiovascular diseases, diabetes mellitus, osteoporosis; but its role in treatment of certain conditions like multiple sclerosis, cognition needs to be assessed further studies. Method: Various reports were taken from review or research articles published in journals, data from various books and other online available literature. Conclusion: The discovery that most tissues and cells in the body have a vitamin D receptor andthat several possess the enzymatic machinery to convert the primary circulating formof vitamin D, 25-hydroxyvitamin D, to the active form, 1,25-dihydroxyvitamin D, hasprovided new insights into the function of this vitamin. Great interest is the roleit can play in decreasing the risk of many chronic illnesses, including common cancers,autoimmune diseases, infectious diseases, and cardiovascular disease.

Keywords:Vitamin D Deficiency, cancer, cardiovascular, vitaminD3, diabetes mellitus, Multiple Sclerosis.


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